Ophthalmology has been a proving ground for emerging machine-learning paradigms in medicine. The efforts of the ophthalmic and computer science communities have yielded thousands of innovative models, exploring tasks ranging from basic science to clinical epidemiology.

The Open Ophthalmology Database was developed in 2023 as the Vision Intelligence Network to provide a systematic means of identifying and implementing machine-learning models in ophthalmology. It leverages natural language processing to survey the published literature for pertinent models and characterize them in terms of their purpose, data substrate, and algorithmic approaches.

Key data cataloged in the database include the following:



Curation relies on hard-coded metadata extraction where possible. Where this is not feasible, the model invokes agentic tools to summarize pertinent data. While we make efforts to check the reliability of these outputs, we note that such tools are fundamentally probabilistic and may generate inaccurate summaries. All entries are linked to their respective publications, and users are advised to refer to the reference for all technical details regarding the model. This database is an experimental research effort and should not be used for clinical decision-making.

Inquiries are welcome at contact@openophthodb.org.